Search results for "Bronchial obstruction"
showing 8 items of 8 documents
Difference in Mortality Risk in Elderly People with Bronchial Obstruction Diagnosed Using a Fixed Cutoff or the Lower Limit of Normal of the FEV1/FVC…
2017
Background: Whether a fixed cutoff or the lower limit of normal of the FEV1/FVC ratio should be used to diagnose bronchial obstruction is still a matter of debate. This issue is particularly important for elderly people. Objectives: We used equations applicable up to 90 years of age to evaluate the mortality of elderly people diagnosed with bronchial obstruction using either a fixed cutoff of 0.7 or the lower limit of normal (LLN). Methods: Participants in the SaRA (Salute Respiratoria nell'Anziano, Italian for "Respiratory Health in the Elderly") study were grouped as follows: FEV1/FVC ≥0.7 and ≥ LLN (n = 535: F-/L-), FEV1/FVC <0.7 but ≥ LLN (n = 118: F+/L-), and FEV1/FVC <0.7 and < LLN (n…
Usage of BODE index to estimate the results of rehabilitation of patients with chronic obstructive lung disease
2008
Abstract: BODE index is the prognostic indicator in chronic obstructive lung disease, in which beyond bronchial obstruction the body mass index, dyspnea and competence exercise are taken into consideration. The indicator consists of few elements: B – BMI, O – obturation, D – dyspnea, E – exercise, taking into consideration various constitutional aspects of disease. The purpose of the paper was usage of BODE index in estimation of results of rehabilitation of patients with Chronic Obstructive Lung Disease. 60 in- hospital patients with chronic obstructive lung disease were examined, in Specialized Hospital MSWiA (Ministry of Interior and Administration) in Glucholazy. The pa-tients, who were…
Airway distensibility by HRCT in asthmatics and COPD with comparable airway obstruction.
2013
Introduction: Decreased airway distensibility (AD) in response to deep inspirations, as assessed by HRCT, has been associated with the severity of asthma and COPD. Aims: The current study was designed to compare the magnitude of AD by HRCT in individuals with asthma and COPD with comparable degrees of bronchial obstruction, and to explore factors that may influence it. Results: We enrolled a total of 12 asthmatics (M/F:7/5) and 8 COPD (7/1) with comparable degree of bronchial obstruction (FEV1% predicted mean±SEM: 69.1 ± 5.2% and 61.2 ± 5.0%, respectively; p = 0.31). Each subject underwent chest HRCT at FRC and at TLC. A total of 701 airways (range 20 to 38 airway per subject; 2.0 to 23.1 m…
Clinical implications of airway hyper-responsiveness in COPD
2006
COPD represents one of the leading causes of mortality in the general population. This study aimed at evaluating the relationship between airway hyperresponsiveness (AHR) and COPD and its relevance for clinical practice. We performed a MEDLINE search that yielded a total of 1919 articles. Eligible studies were defined as articles that addressed specific aspects of AHR in COPD, such as prevalence, pathogenesis, or prognosis. AHR appears to be present in at least one out of two individuals with COPD. The occurrence of AHR in COPD is influenced by multiple mechanisms, among which impairment of factors that oppose airway narrowing plays an important role. The main determinants of AHR are reduct…
Development of New Antiasthmatic Drugs from Traditional Medicine?
1991
Several plants are used in traditional medicine in the treatment of bronchial asthma. We are trying to identify the active compound(s) and their mode of action.